﻿<?xml version="1.0" encoding="UTF-8"?>
<MIBBI_module xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://mibbi.sourceforge.net/foundry/MIBBI_module_v1.3.xsd">
	<module_name>MIRIAM</module_name>
	<module_version>n/a</module_version>
	<module_reference>http://biomodels.net/miriam/</module_reference>
	<module_notes>Taken direct from the web-available version (HTML) on 2011-06-14 by Chris Taylor (chrisftaylor@gmail.com).</module_notes>
	<structure_component>
		<structure_component_full_name>Reference correspondence</structure_component_full_name>
		<content_component>
			<content_component_full_name>The model must be encoded in a public, standardized, machine-readable format</content_component_full_name>
			<content_component_examples>SBML, CellML, GENESIS</content_component_examples>
		</content_component>

		<content_component>
			<content_component_full_name>The model must comply with the standard in which it is encoded</content_component_full_name>
		</content_component>

		<content_component>
			<content_component_full_name>The model must be clearly related to a single reference description</content_component_full_name>
			<content_component_notes>If a model is composed from different parts, there should still be a description of the derived/combined model.</content_component_notes>
		</content_component>

		<content_component>
			<content_component_full_name>The encoded model structure must reflect the biological processes listed in the reference description</content_component_full_name>
		</content_component>

		<content_component>
			<content_component_full_name>The model must be instantiated in a simulation</content_component_full_name>
			<content_component_notes>All quantitative attributes have to be defined, including initial conditions.</content_component_notes>
		</content_component>

		<content_component>
			<content_component_full_name>When instantiated, the model must be able to reproduce all results given in the reference description within an epsilon</content_component_full_name>
			<content_component_notes>(algorithms, round-up errors)</content_component_notes>
		</content_component>

	</structure_component>

	<structure_component>
		<structure_component_full_name>Attribution annotation</structure_component_full_name>
		<content_component>
			<content_component_full_name>The model has to be named</content_component_full_name>
		</content_component>

		<content_component>
			<content_component_full_name>A citation of the reference description must be joined</content_component_full_name>
			<content_component_notes>The citation should permit to identify the authors of the model.</content_component_notes>
			<content_component_examples>complete citation, unique identifier, unambigous URL</content_component_examples>
		</content_component>

		<content_component>
			<content_component_full_name>The name and contact of model creators must be joined</content_component_full_name>
		</content_component>

		<content_component>
			<content_component_full_name>The date and time of creation and last modification should be specified</content_component_full_name>
			<content_component_notes>A history is useful but not required.</content_component_notes>
		</content_component>

		<content_component>
			<content_component_full_name>The model should be linked to a precise statement about the terms of distribution</content_component_full_name>
			<content_component_notes>MIRIAM does not require “freedom of use” or “no cost”.</content_component_notes>
		</content_component>

	</structure_component>

	<structure_component>
		<structure_component_full_name>External resource annotation</structure_component_full_name>
		<content_component>
			<content_component_full_name>The annotation must permit to unambiguously relate a piece of knowledge to a model constituent</content_component_full_name>
		</content_component>

		<content_component>
			<content_component_full_name>The referenced information should be described using a triplet</content_component_full_name>
			<content_component_notes>(i) The data type should be written as a Uniform Resource Identifier (URI). (ii) The identifier is analysed within the framework of the data type. (iii) Data type and identifier can be combined in a single URI, such as: urn:miriam:dataType:identifier. For example: urn:miriam:uniprot:P62158. (iv) Qualifiers (optional) should refine the link between the model constitutent and the piece of knowledge: “has a”, “is version of”, “is homolog to”, etc.</content_component_notes>
			<content_component_syntax>{data type, identifier, qualifier}</content_component_syntax>
		</content_component>

		<content_component>
			<content_component_full_name>The community has to agree on a set of standard valid URIs</content_component_full_name>
			<content_component_notes>A database and the associated API (Web Services) have been developed at the EBI to provide the generation and interpretation of URIs.</content_component_notes>
		</content_component>

	</structure_component>

</MIBBI_module>
