﻿<?xml version="1.0" encoding="UTF-8"?>
<MIBBI_module xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://mibbi.sourceforge.net/foundry/MIBBI_module_v1.3.xsd">
	<module_name>MIMIx</module_name>
	<module_version>1.1.2</module_version>
	<module_reference>http://www.psidev.info/index.php?q=wiki/Molecular_Interactions</module_reference>
	<module_notes>Taken direct from the web-available version 1.1.2 (PDF) on 2011-06-05 by Chris Taylor (chrisftaylor@gmail.com)</module_notes>
	<structure_component>
		<structure_component_full_name>Manuscript</structure_component_full_name>
		<structure_component_notes>A submission must contain the essential administrative information</structure_component_notes>
		<content_component>
			<content_component_full_name>Contact email</content_component_full_name>
		</content_component>
		<content_component>
			<content_component_full_name>Publication title</content_component_full_name>
		</content_component>
		<content_component>
			<content_component_full_name>First author</content_component_full_name>
		</content_component>
		<content_component>
			<content_component_full_name>Publication identifier</content_component_full_name>
		</content_component>
	</structure_component>
	<structure_component>
		<structure_component_full_name>Experiment</structure_component_full_name>
		<structure_component_notes>Each experimental setup should be described separately, with the following parameters</structure_component_notes>
		<content_component>
			<content_component_full_name>Host system</content_component_full_name>
			<content_component_definition>The host organism in which the interaction took place.</content_component_definition>
			<content_component_notes>Identificaton by NCBI tax id. Further specification of cell line or tissue is recommended.</content_component_notes>
			<content_component_examples>Yeast (TaxID:4932)</content_component_examples>
		</content_component>
		<content_component>
			<content_component_full_name>Interaction detection method</content_component_full_name>
			<content_component_definition>The method by which the interaction has been detected</content_component_definition>
			<content_component_examples>two hybrid (MI:0018)</content_component_examples>
			<content_component_ontology_link_list>
				<content_component_ontology_link>
					<ontology_uri>http://www.obofoundry.org/cgi-bin/detail.cgi?id=psi-mi</ontology_uri>
					<ontology_name>PSI-MI</ontology_name>
					<ontology_term_accession>MI:0001</ontology_term_accession>
					<ontology_term_as_used>interaction detection method</ontology_term_as_used>
					<ontology_term_usage_description>Root term</ontology_term_usage_description>
				</content_component_ontology_link>
			</content_component_ontology_link_list>
		</content_component>
		<content_component>
			<content_component_full_name>Participant Identification method</content_component_full_name>
			<content_component_definition>The method by which the interaction participants have been determined</content_component_definition>
			<content_component_examples>nucleotide sequence (MI:0078)</content_component_examples>
			<content_component_ontology_link_list>
				<content_component_ontology_link>
					<ontology_uri>http://www.obofoundry.org/cgi-bin/detail.cgi?id=psi-mi</ontology_uri>
					<ontology_name>PSI-MI</ontology_name>
					<ontology_term_accession>MI:0002</ontology_term_accession>
					<ontology_term_as_used>participant identification method</ontology_term_as_used>
					<ontology_term_usage_description>Root term</ontology_term_usage_description>
				</content_component_ontology_link>
			</content_component_ontology_link_list>
		</content_component>
	</structure_component>
	<structure_component>
		<structure_component_full_name>Interaction</structure_component_full_name>
		<structure_component>
			<structure_component_full_name>Participant list</structure_component_full_name>
			<structure_component_definition>The list of all molecules participating in the interaction.</structure_component_definition>
			<structure_component_notes>The list can contain one to many elements. Each molecule should be characterised by</structure_component_notes>
			<content_component>
				<content_component_full_name>Database</content_component_full_name>
				<content_component_examples>UniProt (MI:0486)</content_component_examples>
				<content_component_ontology_link_list>
					<content_component_ontology_link>
						<ontology_uri>http://www.obofoundry.org/cgi-bin/detail.cgi?id=psi-mi</ontology_uri>
						<ontology_name>PSI-MI</ontology_name>
						<ontology_term_accession>MI:0444</ontology_term_accession>
						<ontology_term_as_used>database citation</ontology_term_as_used>
						<ontology_term_usage_description>Root term</ontology_term_usage_description>
					</content_component_ontology_link>
				</content_component_ontology_link_list>
			</content_component>
			<content_component>
				<content_component_full_name>Accession number from that database</content_component_full_name>
				<content_component_examples>P48551</content_component_examples>
			</content_component>
			<content_component>
				<content_component_full_name>Version number</content_component_full_name>
				<content_component_usage_list>
					<content_component_usage>
						<optionality>should</optionality>
					</content_component_usage>
				</content_component_usage_list>
			</content_component>
			<content_component>
				<content_component_full_name>Name</content_component_full_name>
				<content_component_definition>The common name of the molecule, as used in the manuscript</content_component_definition>
				<content_component_examples>IFN-aRBL</content_component_examples>
			</content_component>
			<content_component>
				<content_component_full_name>The species of origin for the molecule</content_component_full_name>
				<content_component_notes>Identified by NCBI tax id.</content_component_notes>
				<content_component_examples>9606</content_component_examples>
			</content_component>
			<content_component>
				<content_component_full_name>Biological role</content_component_full_name>
				<content_component_definition>The biological role of the molecule in the interaction.</content_component_definition>
				<content_component_examples>neutral component (MI:0497)</content_component_examples>
				<content_component_ontology_link_list>
					<content_component_ontology_link>
						<ontology_uri>http://www.obofoundry.org/cgi-bin/detail.cgi?id=psi-mi</ontology_uri>
						<ontology_name>PSI-MI</ontology_name>
						<ontology_term_accession>MI:0500</ontology_term_accession>
						<ontology_term_as_used>biological role</ontology_term_as_used>
						<ontology_term_usage_description>Root term</ontology_term_usage_description>
					</content_component_ontology_link>
				</content_component_ontology_link_list>
			</content_component>
			<content_component>
				<content_component_full_name>Experimental role</content_component_full_name>
				<content_component_definition>The experimental role of the molecule in the interaction.</content_component_definition>
				<content_component_examples>bait (MI:0496)</content_component_examples>
				<content_component_ontology_link_list>
					<content_component_ontology_link>
						<ontology_uri>http://www.obofoundry.org/cgi-bin/detail.cgi?id=psi-mi</ontology_uri>
						<ontology_name>PSI-MI</ontology_name>
						<ontology_term_accession>MI:0495</ontology_term_accession>
						<ontology_term_as_used>biological role</ontology_term_as_used>
						<ontology_term_usage_description>Root term</ontology_term_usage_description>
					</content_component_ontology_link>
				</content_component_ontology_link_list>
			</content_component>
		</structure_component>
		<content_component>
			<content_component_full_name>Confidence</content_component_full_name>
			<content_component_definition>A confidence value attributed to the interaction.</content_component_definition>
			<content_component_notes>The confidence attribution system must be described in the manuscript. Ideally, the raw data for the confidence assignment should be available. </content_component_notes>
			<content_component_usage_list>
				<content_component_usage>
					<optionality>should</optionality>
				</content_component_usage>
			</content_component_usage_list>
		</content_component>
	</structure_component>
</MIBBI_module>
